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Geroprotective effects of diet and exercise plus metformin in frail older veterans with obesity: The DEMFOS randomized trial protocol

Nina Klonis et al. Geroprotective effects of diet and exercise plus metformin in frail older veterans with obesity: The DEMFOS randomized trial protocol Contemporary Clinical Trials.

Publication Date
April 18, 2026

How Analyze was Used
“Muscle volume is quantified for each slice using AnalyzeDirect software (version 14.0; Mayo Clinic, Rochester, MN, USA), and the sum of the 10 slices represents muscle volume within the 10-cm region of interest.”

Keywords
Frailty, Obesity, Metformin, Antidiabetic agent, Geroprotective properties, Cellular mechanisms of aging

Author Affiliation(s)
Baylor College of Medicine, Houston, Texas, USA

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