McAlindon T, LaValley M, Schneider E, Nuite M, Lee JY, Price LL, Lo G, Dawson-Hughes B. Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial. JAMA. January 2013;309(2):155-162.
Full Text – Open Access
Publication Date
January 2013
How Analyze was Used
“We delineated the 3-dimensional cartilage segments using ANALYZE.”
Keywords
Aged
Cartilage/pathology
Dietary Supplements
Disease Progression
Double-Blind Method
Female
Humans
Knee Joint/pathology
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Osteoarthritis, Knee/complications/drug therapy/pathology
Pain/etiology/prevention & control
Treatment Outcome
Vitamin D/therapeutic use
Vitamins/therapeutic use
Author Affiliation(s)
Division of Rheumatology, Tufts Medical Center, Boston, MA, US. (TM, JYL, MN)
Boston University School of Public Health, Crosstown Center, Boston, MA, US.. (ML)
Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, US. (ES)
Biostatistics Research Center in the Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, US.. (LLP)
Michael E. DeBakey Veterans Affairs Medical Center, Medical Care Line and Research Care Line; Houston VA Health Services Research and Development Center of Excellence, and Section of Immunology, Allergy, and Rheumatology, Department of Medicine, Baylor College of Medicine, Houston, TX, US. (GL)
Jean Mayer USDA Human Nutrition Research Center on Aging, at Tufts University, Boston, MA, US.. (BDH)
ID# 303
Tags: Aged, Cartilage/pathology, Dietary Supplements, Disease Progression, Double-Blind Method, Female, Humans, Knee Joint/pathology, Knee Osteoarthritis/complications/drug therapy/pathology, Magnetic Resonance Imaging (MRI), Male, Middle Aged, Pain/etiology/prevention & control, Treatment Outcome, Vitamin D/therapeutic use, Vitamins/therapeutic use