AnalyzeDirect Falcone GJ, Biffi A, Devan WJ, Brouwers HB, Anderson CD, Valant V, Ayres AM, Schwab K, Rost NS, Goldstein JN, Viswanathan A, Greenberg SM, Selim M, Meschia JF, Brown DL, Worrall BB, Silliman SL, Tirschwell DL, Rosand J. Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage. Stroke. February 2013;44(2):321-326.
Full Text – Open Access
Publication Date
February 2013
How Analyze was Used
“ICH BHVs [baseline hematoma values] were centrally assessed at the Massachusetts General Hospital (the coordinating center) using Alice … and Analyze 9.0.”
Keywords
Aged
Aged, 80 and over
Alleles
Blood Pressure/genetics
Cerebral Hemorrhage/genetics/pathology/physiopathology
Cohort Studies
Female
Genome-Wide Association Study/methods
Genotype
Hematoma, Epidural, Cranial/genetics/pathology/physiopathology
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide/genetics
Prospective Studies
Treatment Outcome
Author Affiliation(s)
Center for Human Genetic Research, Massachusetts General Hospital (MGH), Boston, MA, US. (GJF, AB, WJD, HBB, CDA, VV, NSR, JR)
Hemorrhagic Stroke Research Group, MGH, Boston, MA, US. (GJF, AB, WJD, HBB, CDA, VV, AMA, KS, NSR, AV, SMG, JR)
Department of Neurology, Division of Neurocritical Care and Emergency Neurology, MGH, Boston, MA, US. (GJF, AB, WJD, HBB, CDA, NSR, JR)
Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, US. (GJF, AB, WJD, HBB, CDA, NSR, JR)
Department of Epidemiology, Harvard School of Public Health, Boston, MA, US. (GJF)
Department of Emergency Medicine, MGH, Boston, MA, US. (JNG)
Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, US. (MS)
Department of Neurology, Mayo Clinic, Jacksonville, FL, US. (JFM)
Stroke Program, Department of Neurology, University of Michigan Health System, Ann Arbor, MI, US. (DLB)
Department of Neurology and Public Health Sciences, University of Virginia Health System, Charlottesville, VA, US. (BBW)
Department of Neurology, University of Florida College of Medicine, Jacksonville, FL, US. (SLS)
Stroke Center, Harborview Medical Center, University of Washington, Seattle, WA, US. (DLT)
ID# 296
Tags: Aged, Aged_80 and over, Alleles, Blood Pressure/genetics, Cerebral Hemorrhage/genetics/pathology/physiopathology, Cohort Studies, Female, Genome-Wide Association Study/methods, Genotype, Hematoma_Epidural_Cranial/genetics/pathology/physiopathology, Humans, Male, Middle Aged, Prospective Studies, Single Nucleotide Polymorphism/genetics, Treatment Outcome