Feng L, Isaac V, Sim S, Ng TP, Krishnan KR, Chee MWL. Associations between elevated homocysteine, cognitive impairment, and reduced white matter volume in healthy old adults. Am J Geriatr Psychiatry. February 2013;21(2):164-172.
Publication Date
February 2013
How Analyze was Used
“Two trained researchers performed manual, interactive volumetry for total intracranial volume,
hippocampal volume (HC), ventricle volume, and WMH using Analyze 7.0 software…on graphic tablets.”
Keywords
Age Factors
Aged
Asian Continental Ancestry Group
Brain/pathology
Cardiovascular Diseases/diagnosis
Cognition Disorders/blood/pathology
Female
Folic Acid/blood
Homocysteine/blood
Humans
Linear Models
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Nerve Fibers, Myelinated/pathology
Neuropsychological Tests
Organ Size
Singapore
Vitamin B 12/blood
Author Affiliation(s)
Gerontological Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. (LF, TPN)
Cognitive Neuroscience Laboratory, Neuroscience and Behavioural Disorders Program, Duke-NUS Graduate Medical School, Singapore. (VI, SS, RRK, MWLC)
ID# 271
Tags: Age Factors, Aged, Asian Continental Ancestry Group, Brain/pathology, Cardiovascular Diseases/diagnosis, Cognition Disorders/blood/pathology, Female, Folic Acid/blood, Homocysteine/blood, Humans, Linear Models, Magnetic Resonance Imaging (MRI), Male, Middle Aged, Myelinated Nerve Fibers/pathology, Neuropsychological Tests, Organ Size, Singapore, Vitamin B 12/blood