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Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences

Bernd Coester et al. Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences Metabolites.

Publication Date
January 8, 2022

How Analyze was Used
“CT scans of mouse carcasses were acquired with a Quantum GX micro-CT (PerkinElmer, Waltham, USA). X-ray settings were at 50 kV with 160 µA current for ideal soft tissue resolution. The full body scan was cropped to the length of the lumbar spine, femur, fat and lean mass was quantified as a representative portion of the whole body with Analyze 12.0 software (AnalyzeDirect, Overland Park, KS, USA).”

Keywords
Amylin, Leptin, Hypothalamus, AgRP, CTR, CALCR, Microglia, IL-6, Energy expenditure, Adiposity, Glucose tolerance

Author Affiliation(s)
University of Zurich, Zurich, Switzerland

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