AnalyzeDirect Galanis E, Anderson SK, Lafky JM, Uhm JH, Giannini C, Kumar SK, Kimlinger TK, Northfelt DW, Flynn PJ, Jaeckle KA, Kaufmann TJ, Buckner JC. Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): a north central cancer treatment group trial. Clin Cancer Res. September 2013;19(17):4816-4823.
Full Text – Open Access
Publication Date
September 2013
How Analyze was Used
“To calculate the apparent diffusion coefficient (ADC), regions of interest were manually traced around all contrast-enhancing tumors, excluding areas of necrosis and hemorrhage, on baseline scans, and on follow-up scans through 2 months’ time using Analyze software.”
Keywords
Adult
Aged
Antibodies, Monoclonal, Humanized/administration & dosage
Antineoplastic Combined Chemotherapy Protocols
Brain Neoplasms/drug therapy/pathology
Disease-Free Survival
Female
Glioblastoma/drug therapy/pathology
Humans
Hypoxia-Inducible Factor 1, alpha Subunit/genetics
Male
Middle Aged
Neoplasm Recurrence, Local/drug therapy/pathology
Neoplastic Cells, Circulating
Niacinamide/administration & dosage/analogs & derivatives
Phenylurea Compounds/administration & dosage
Polymorphism, Single Nucleotide
Proportional Hazards Models
Tumor Markers, Biological/genetics
Vascular Endothelial Growth Factor A/genetics
Vascular Endothelial Growth Factor Receptor-2/genetics
Author Affiliation(s)
Mayo Clinic Rochester, MN, US. (EG, SKA, JML, JHU, CG, SKK, TKK, TJK, JCB)
Metro-Minnesota Community Clinical Oncology Program, St. Louis Park, MN, US. (PJF)
Mayo Clinic Arizona, Scottsdale, AZ, US. (DWN)
Mayo Clinic Florida, Jacksonville, FL, US. (KAJ)
ID# 279
Tags: Adult, Aged, alpha Subunit Hypoxia-Inducible Factor 1/genetics, Antineoplastic Combined Chemotherapy Protocols, Biological Tumor Markers/genetics, Brain Neoplasms/drug therapy/pathology, Circulating Neoplastic Cells, Disease-Free Survival, Female, Glioblastoma/drug therapy/pathology, Humanized Antibodies_Monoclonal /administration & dosage, Humans, Local Neoplasm Recurrence/drug therapy/pathology, Male, Middle Aged, Niacinamide/administration & dosage/analogs & derivatives, Phenylurea Compounds/administration & dosage, Proportional Hazards Models, Single Nucleotide Polymorphism, Vascular Endothelial Growth Factor A/genetics, Vascular Endothelial Growth Factor Receptor-2/genetics