R. Vitorino1, S.-P. Hojjat1,2, C.G. Cantrell3, A. Feinstein4,5, L. Zhang1, L. Lee6,7, P. O’Connor7, T.J. Carroll3,8, R.I. Aviv1,2. Regional Frontal Perfusion Deficits in Relapsing-Remitting Multiple Sclerosis with Cognitive Decline. American Journal of Neuroradiology. 19 May 2016.
Full Text – Open Access
Publication Date
May 2016
How Analyze was Used
“Lesions were manually traced with Analyze 8.0 software (AnalyzeDirect, Overland Park, Kansas) by an experienced clinician (10 years’ experience) by using phase-sensitive inversion recovery for cortical lesion tracing and proton-density/T2 and T1 scans for WM T2 hyperintense lesions and T1 black hole tracing, respectively.”
Keywords
Multiple sclerosis
Cerebral perfusion
Biomarker
Cognitive impairment
Cortical dysfunction
Author Affiliation(s)
1Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
2Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada
3Department of Biomedical Engineering, Northwestern University, Chicago, Illinois
4Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
5Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
6Department of Neurology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
7Department of Medicine, University of Toronto, Toronto, Ontario, Canada
8Department of Radiology, Northwestern University, Chicago, Illinois