AnalyzeDirect Plassman BL, Welsh-Bohmer KA, Bigler ED, Johnson SC, Anderson CV, Helms MJ, Saunders AM, Breitner JCS. Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition. Neurology. April 1997;48(4):985-989.
Publication Date
April 1997
How Analyze was Used
“Hippocampal volumes were measured on coronal sections using the ANALYZE program … as described in detail elsewhere. Briefly, hippocampal boundaries were defined with the aid of an ANALYZE multispectral segmentation process in combination with brain and MR atlases.”
Keywords
Alleles
Apolipoprotein E4
Apolipoproteins E/genetics
Cognition
Female
Genotype
Hippocampus/anatomy & histology
Humans
Male
Middle Aged
Reference Values
Twins
Author Affiliation(s)
Department of Psychiatry, Duke University Medical Center, Durham, NC, US. (BLP, KAWB, MJH, JCSB)
Joseph and Kathleen Bryan Alzheimer’s Disease Research Center, Duke University Medical Center, Durham, NC, US. (BLP, KAWB, AMS, JCSB)
Department of Psychology, Brigham Young University, Salt Lake City, UT. (EDB, SCJ, CVA)
ID# 2992
Tags: Alleles, Apolipoprotein E4, Apolipoproteins E/genetics, Cognition, Female, Genotype, Hippocampus/anatomy & histology, Humans, Male, Middle Aged, Reference Values, Twins