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Lingle WL, Lutz WH, Ingle JN, Maihle NJ, Salisbury JL. Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity. Proc Natl Acad Sci U S A. March 1998;95(6):2950-2955.

Full Text – Open Access

Publication Date
March 1998

How Analyze was Used
“Raw digital fluorescence data were imported into Analyze, an image processing program …, and signal intensity threshold was adjusted so that centrin-labeled spots were discrete objects in the green channel and nuclei were discrete objects in the red channel.”

Keywords
Adenocarcinoma/genetics/pathology/ultrastructure
Aneuploidy
Breast Neoplasms/genetics/pathology/ultrastructure
Cell Polarity/genetics
Centrioles/pathology
Centrosome/pathology/ultrastructure
Epithelial Cells/pathology
Female
Humans
Hypertrophy
Neoplasm Proteins
Phosphoproteins
Phosphorylation

Author Affiliation(s)
Tumor Biology Program, Mayo Clinic Foundation, Rochester, MN 55905, US.

ID# 2980

Tags: Adenocarcinoma/genetics/pathology/ultrastructure, Aneuploidy, Breast Neoplasms/genetics/pathology/ultrastructure, Cell Polarity/genetics, Centrioles/pathology, Centrosome/pathology/ultrastructure, Epithelial Cells/pathology, Female, Humans, Hypertrophy, Neoplasm Proteins, Phosphoproteins, Phosphorylation