Morgane Dos Santos et al. Refining the mandibular osteoradionecrosis rat model by in vivo longitudinal µCT analysis Scientific Reports.
November 15, 2021
How Analyze was Used
“Images were analyzed using AnalyzePro version 1.0 and Analyze version 12.0 software (AnalyzeDirect; https://analyzedirect.com) for 3D analysis (volume quantification)…For 3D µCT image analysis, we quantified the bone volume on in vivo images and the bone and vessel volumes on ex vivo images. When quantifying bone volume on the in vivo images, the semi-automatic software option was used to segment each mandible as an object, always using the same threshold range for all rats for comparison purposes. Then, we manually excluded the incisors by contouring, on the frontal section, 1 slice in 4, and by propagating the volume following this section. The resulting total bone volume on in vivo images factors in bone and molars.”
Biological physics, Oral diseases
IRSN, Institute of Radioprotection and Nuclear Safety, Fontenay-aux-Roses, France