Yuka Kinoshita et al. Gene therapy using adeno-associated virus serotype 8 encoding TNAP-D10 improves the skeletal and dentoalveolar phenotypes in Alpl−/− mice Bone Research.
June 2, 2021
How Analyze was Used
“Reconstructed images were calibrated to 5 known densities of hydroxyapatite and analyzed using AnalyzePro (version 1.0; AnalyzeDirect, Overland Park, KS). For femurs, trabecular and cortical bones were segmented at 350 and 650 mg HA/cm3, respectively. The trabecular bone was traced using 50 slices (total of 0.5 mm) proximal to the distal femur growth.”
Bone histomorphometry, Bone μCT, Dental biology, Genetic animal models, Osteomalacia and rickets
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA