Xuyi Yue1, Hongjun Jin1, Zonghua Luo1, Hui Liu1, Xiang Zhang1, Ethan D. McSpadden2, Linlin Tian3, Hubert P. Flores3, Joel S. Perlmutter1,3, Stanley M. Parsons2, Zhude Tu1. Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (-)-[18F]TZ3108 in rodent and the nonhuman primate brain. Bioorganic & Medicinal Chemistry. January 16 2017.
How Analyze was Used
“The MRI (MPRAGE) was co-registered to the baseline PET image. All volume of interest (VOI) were drawn on the MPRAGE image using Vidi or Analyze program (AnalyzeDirect Inc., Overland Park, KS). Three-dimensional VOIs were transformed to the PET space and then overlaid on all reconstructed PET images to obtain TACs.”
Fluorine-18, Enantiomer, σ1 receptor, PET imaging
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA
2Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA
3Department of Neurology, Washington University School of Medicine, St Louis, MO, USA